Pre-cancious penile intraepithelial neoplasia. Modern terminology according to the 2016 WHO Classification of Tumors of the Urinary System and Male Genital Organs

Modern vision of pre-cancious penile intraepithelial neoplasia contained in the 2016 WHO Classification of Tumors of the Urinary System and Male Genital Organs was studied. New approaches to systematization of pre-cancious epithelial tumors of penis were reviewed in the fifth chapter of the 2016 WHO Classification called «Tumours of the penis» in section Precursor lesions. In this chapter two nosological units such as penile intraepithelial neoplasia associated with HPV infection and differentiated penile intraepithelial neoplasia not associated with NPV were proposed. We analysed patients with papulosis bowenoid, leukoplakia, penile lichen sclerosus, pseudoepitheliomatous keratotic and micaceous balanitis in Main Military Clinical Hospital named after N.N. Burdenko in accordance with different histopathological types of penile intraepithelial neoplasia. Penile intraepithelial neoplasia associated with HPV is identified in cases of papulosis bowenoid. Differential penile intraepithelial neoplasia can be found in clinical dignosis of leukoplakia, penile lichen sclerosus, pseudoepitheliomatous keratotic and micaceous balanitis.

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