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Морфин при остром коронарном синдроме и инфаркте миокарда: pro et contra

https://doi.org/10.36107/hfb.2021.i1.s92

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Аннотация

В обзоре обобщены данные литературы по применению морфина у пациентов с острым коронарным синдромом и инфарктом миокарда. Кратко сообщается о возможности назначения морфина в таких клинических ситуациях в соответствии с действующими рекомендациями Организации Американской Коллегии Кардиологов/Американской Ассоциации Сердца и Европейского Общества Кардиологов. После описания фармакологических свойств морфина, подробно обсуждаются его положительные эффекты: обезболивание, улучшение гемодинамики, предполагаемое влияние на ремоделирование миокарда. Для полноценного представления о препарате приводится информация о влиянии морфина на клинические исходы – смерть, рецидив инфаркта миокарда, инсульт, кровотечение. Обзор содержит важную информацию о взаимодействии морфина с антитромбоцитарными препаратами, назначаемыми пациентам с острым коронарным синдромом и инфарктом миокарда. В заключение статьи обсуждаются необходимые варианты оптимального обезболивания пациентов с острым коронарным синдромом и инфарктом миокарда, а также востребованность в изучении новых антитромбоцитарных препаратов в этих условиях.

Об авторах

Григорий Анатольевич Игнатенко
ГОО ВПО «Донецкий национальный медицинский университет имени М. Горького»
Украина

Ректор ГОО ВПО ДОННМУ ИМЕНИ М. ГОРЬКОГО, заведующий кафедрой пропедевтики внутренних болезней, профессор, д.м.н., чл.-корр. НАМН Украины



Геннадий Геннадьевич Тарадин
ГОО ВПО "ДОННМУ ИМЕНИ М.ГОРЬКОГО" ГУ "Институт неотложной и восстановительной хирургии им. В.К. Гусака"
Украина

заведующий кафедрой терапии им. проф. А.И. Дяыка ФИПО,

отдел кардиологии и кардиохирургии, старший научный сотрудник



Ирина Валериевна Ракитская
ГОО ВПО "ДОННМУ ИМЕНИ М.ГОРЬКОГО"
Украина

доцент кафедры терапии ФИПО им. проф. А.И. Дядыка, к.м.н.



Виктория Борисовна Гнилицкая
ГОО ВПО "ДОННМУ ИМЕНИ М.ГОРЬКОГО"
Украина

доцент кафедры терапии ФИПО им. проф. А.И. Дядыка, к.м.н.



Светлана Олеговна Куликова
ГОО ВПО "ДОННМУ ИМЕНИ М.ГОРЬКОГО"
Украина


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Рецензия

Для цитирования:


Игнатенко Г.А., Тарадин Г.Г., Ракитская И.В., Гнилицкая В.Б., Куликова С.О. Морфин при остром коронарном синдроме и инфаркте миокарда: pro et contra. Health, Food & Biotechnology. 2021;3(1):13-29. https://doi.org/10.36107/hfb.2021.i1.s92

For citation:


Ignatenko G.A., Taradin G.G., Rakitskaya I.V., Gnilitskaya V.B., Kulikova S.O. Morphine in acute coronary syndrome and myocardial infarction: pro et contra. Health, Food & Biotechnology. 2021;3(1):13-29. (In Russ.) https://doi.org/10.36107/hfb.2021.i1.s92

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